Bitter melon or bitter gourd is a staple food in many parts of the world. It belongs to the Cucurbitaceae family, which includes squash, cucumbers, and melons. This fruit is indigenous to Africa but largely produced in various countries in Southeast Asia. Due to the beneficial properties of bitter melon, its extract is included in natural food supplement. It is used as a cosmetic additive and pharmaceutical ingredient. The antioxidants in bitter melon protects cells against damage and reduce the signs of ageing.